Prokinetic Drugs

The list below provides some examples of the articles available in the InsHeal Content Repository on drugs that belong to a group called prokinetic drugs, which increase the movement of the digestive tract. For further details and sample articles, please reach out to us at: insheal@insiwi.co.in.

Drug	Description
Cisapride	Cisapride is a prokinetic drug that increases the movement of the entire digestive tract. It may cause abnormal heart rhythms as a side effect, especially when combined with certain other drugs. It is no longer available in the United States.
Domperidone	Domperidone is a prokinetic drug that increases the movement of the upper digestive tract. It is effective in the treatment of reflux symptoms and vomiting. Unlike metoclopramide, it does not affect muscle tone.
Levosulpiride	Levosulpiride is a prokinetic and an anti-psychotic drug. It is available in some countries in combination with a proton pump inhibitor to treat dyspepsia.
Metoclopramide	Metoclopramide is a prokinetic drug that increases the movement of the upper digestive tract. It is effective in the treatment of reflux symptoms and vomiting. It is associated with several side effects such as increased muscle tone, changes in heart rate and even cardiac arrest.
Mosapride	Mosapride is a prokinetic drug that increases the movement of the digestive tract and can prevent reflux from the stomach into the lower esophagus. It is not effective in vomiting.
Prucalopride	Prucalopride is a prokinetic that is used to treat chronic constipation of unknown cause. It should not be used in patients with end-stage kidney disease.
Tegaserod	Tegaserod is a prokinetic drug that increases the movement of the digestive tract and can prevent reflux from the stomach into the lower esophagus. It is used to treat irritable bowel syndrome with predominant constipation in women less than 65 years of age. It is associated with several serious adverse events and should therefore be used with caution.

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Disclaimer: The content provided on this site is meant for informational purposes only and not intended to replace the relationship between the doctor and the patient. It should not be used for self-treatment by patients or by doctors to treat patients. Consult your doctor before using any of the above information.